Rethinking brain health

We are on a mission to change the way the world thinks about brain health.

Oxford Brain Diagnostics is committed to analysing the cellular structure of the brain in a way no one else can, to support drug development and aid clinicians around the world in their fight to defeat Alzheimer’s and other neurodegenerative conditions.

The Challenge

Our novel technology assesses brain health based on changes in the cellular structure.

Our pioneering approach, and novel measures unlock unique insights that enable us to predict, detect, quantify, track and differentiate neurodegenerative conditions.

This gives us the potential to revolutionise how people think about brain health.

Our solution

Supporting more efficient drug development and personalised patient care.

Previously inaccessible insights unlocked by our proprietary technology will support more targeted, efficient drug development.

Our Science

Our products

Pharma/Biotech

  • Measures you can trust
  • Get more from your MRI
  • Run targeted, more efficient clinical trials
  • Efficient use of technology across multiple conditions

Our products

Clinical

  • Supporting patient care
  • Helping clinicians in their diagnosis
  • Differential patterns of brain changes
  • Accurately tracking changes
  • Proactive brain health

Our products

Latest news

Oxford Brain Diagnostics Advances Vision for Measuring Brain Health and Neurodegenerative Disease with Five New Studies at AAIC 2026
News Release
15 July 2026

New findings demonstrate the potential of OBD's MRI-based Cortical Disarray Measurement (CDM®) technology to support patient identification, disease characterization, treatment monitoring, and therapeutic development across Alzheimer's disease

New MRI Research Unlocks Earlier Detection of Parkinson’s Disease Microstructural Changes
News Release
14 April 2026

A groundbreaking study has identified a new way to detect the earliest signs of Parkinson’s disease (PD) using advanced brain imaging. The research (a collaboration involving Oxford Brain Diagnostics and AbbVie) demonstrates that diffusion MRI can reveal microscopic "disarray" in the brain’s cortex years before traditional symptoms appear or standard MRI scans show any change.

Caladrix and Oxford Brain Diagnostics partner on Phase 1b Trial of C-001, an ABCC1 Activator, in Alzheimer’s Disease
News Release
13 January 2026

Caladrix and Oxford Brain Diagnostics Ltd Partner to Incorporate Advanced MRI Biomarker (CDM® Cortical Disarray Measurement) as a New Translational Imaging Endpoint in the Forthcoming Phase 1b Trial of C-001, an ABCC1 Activator, in Alzheimer’s Disease.

INmune Bio Reports New Phase 2 Grey Matter Imaging Data at CTAD Conference Reinforcing XPro1595’s Evidence Base in High-Inflammation Alzheimer's Patients
News Release
11 December 2025

Using CDM PerpPD+, a next-generation MRI imaging analysis that quantifies the diffusion components of water molecules that are perpendicular to the cortical gray matter’s minicolumns in the brain (PerpDP+, from Oxford Brain Diagnostics), investigators observed a trend towards slowed neurodegeneration progression in patients receiving XPro1595. These analyses focused on participants with early AD and high inflammatory burden (ADi), including the dose-compliant subgroup.